Preliminary experience with inhaled milrinone in cardiac surgery☆
نویسندگان
چکیده
منابع مشابه
Preliminary experience with inhaled milrinone in cardiac surgery.
BACKGROUND Inhaled administration of milrinone reduces pulmonary artery pressure. Pulmonary hypertension (PH) and right heart failure are associated with difficult separation from cardiopulmonary bypass (CPB). Therefore, inhaled milrinone could facilitate separation from CPB. OBJECTIVE To determine the impact and timing of administration of inhaled milrinone. METHODS A retrospective analysi...
متن کاملIntravenous milrinone in cardiac surgery.
Phosphodiesterase inhibitors including milrinone produce positive inotropic effects by slowing the hydrolysis of cyclic adenosine monophosphate in the myocardium. With a loading dose of 50 microg/kg followed by an infusion of 0.5 microg x kg(-1) x min(-1), milrinone increases stroke volume index and left ventricular velocity of circumferential fiber shortening after weaning from cardiopulmonary...
متن کاملLevosimendan versus milrinone for pediatric cardiac surgery
BACKGROUND: Our aim is to check effectiveness of intravenous Levosimendan in comparison with intravenous Milrinone in congenital heart surgery with cardiopulmonary bypass. MATERIALS AND METHODS: 50 Paediatric patients between 2 months to 12 years of age divided into two groups. Group L (n=25) received inj. levosimendan 12μg/kg over 10 minutes1 after cross clamp removal and 0.1μg/kg/min started ...
متن کاملDisposition of milrinone in patients after cardiac surgery.
We have evaluated the disposition of milrinone in seven patients with low cardiac output after elective cardiac surgery involving cardiopulmonary bypass. Patients received a loading dose of milrinone 50 micrograms kg-1 given over 10 min followed immediately by an infusion of 0.5 microgram kg-1 min-1, continued for a minimum of 5 h. Plasma concentrations of milrinone were measured at designated ...
متن کاملInhaled nitroglycerin versus inhaled milrinone in children with congenital heart disease suffering from pulmonary artery hypertension.
OBJECTIVE The aim of the present study was to compare the acute effects of inhaled milrinone and inhaled nitroglycerin on pulmonary and systemic hemodynamics in children with acyanotic congenital heart disease (left-to-right shunt) and pulmonary artery hypertension. DESIGN Randomized clinical trial. SETTING Catheterization laboratory of a tertiary care hospital. PARTICIPANTS Thirty-five c...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2007
ISSN: 1010-7940
DOI: 10.1016/j.ejcts.2007.02.019